{"entity":{"id":"nct03367572","kind":"trial","name":"Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer","aka":[],"tldr":"A phase 3 trial of Dexamethasone, Palonosetron and Netupitant and palonosetron in Breast cancer, run by University of Rochester NCORP Research Base, completed.","summary":"Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer is a phase 3 interventional study registered as NCT03367572 by University of Rochester NCORP Research Base, with 1363 participants recorded, started 2018-04-19 and reaching its primary completion in 2024-04-13. Interventions recorded: Dexamethasone, Laboratory Biomarker Analysis, Netupitant/Palonosetron Hydrochloride, Olanzapine, Placebo, Prochlorperazine, Quality-of-Life Assessment. Conditions recorded: Breast Carcinoma.\n\nLinked to the drug Netupitant and palonosetron because the registry names it among its interventions and Breast cancer among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT03367572","url":"https://clinicaltrials.gov/study/NCT03367572"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["dexamethasone","palonosetron","netupitant-palonosetron"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03367572","phase":"3","setting":"Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer","sponsor":"University of Rochester NCORP Research Base","enrolled":1363,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03367572/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"drug":[{"id":"dexamethasone","kind":"drug","name":"Dexamethasone","route":"/drugs/dexamethasone/"},{"id":"netupitant-palonosetron","kind":"drug","name":"Netupitant and palonosetron","route":"/drugs/netupitant-palonosetron/"},{"id":"palonosetron","kind":"drug","name":"Palonosetron","route":"/drugs/palonosetron/"}]}}