{"entity":{"id":"nct03413254","kind":"trial","name":"Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases","aka":["COLOPEC-II"],"tldr":"A phase 3 trial in colorectal cancer, run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), active but no longer recruiting.","summary":"Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases is a phase 3, randomised interventional study registered as NCT03413254 by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), with a registry enrolment figure of 389 participants, started 2018-03-01 and due to reach its primary completion in 2025-03-01. Interventions recorded: Routine follow-up; Second look DLS; Third look DLS. Conditions listed: Colorectal Cancer; Peritoneal Metastases. Primary outcome: Proportion of peritoneal metastases detected after a negative second look DLS. Colorectal eligibility wording from the registry: \"* Curative intent resection of pT4a,bN0-2M0 colon cancer or rectosigmoid cancer above the peritoneal reflection, with or without adjuvant systemic therapy;\". Sites: Netherlands. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT03413254","url":"https://clinicaltrials.gov/study/NCT03413254"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":["robotic-surgery"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03413254","phase":"3","setting":"Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases; the COLOPEC-II Randomized Multicentre Trial","sponsor":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","enrolled":389,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03413254/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"technology":[{"id":"robotic-surgery","kind":"technology","name":"Robotic & minimally invasive surgery","route":"/technologies/robotic-surgery/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}