{"entity":{"id":"nct03491683","kind":"trial","name":"INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)","aka":[],"tldr":"A phase 1/2 trial of INO-5401, Cemiplimab and Temozolomide in glioma & glioblastoma, run by Inovio Pharmaceuticals, active and no longer recruiting.","summary":"INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM) is a phase 1/2 interventional study registered as NCT03491683 by Inovio Pharmaceuticals, with 52 participants enrolled, started 2018-05-31 and due to reach its primary completion in 2026-12-31. Interventions recorded: INO-5401, INO-9012, Cemiplimab, Radiation Therapy and Temozolomide.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT03491683","url":"https://clinicaltrials.gov/study/NCT03491683"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["glioblastoma"],"sections":[],"technologies":[],"targets":[],"drugs":["ino-5401","cemiplimab","temozolomide"],"companies":["inovio"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT03491683","phase":"1/2","setting":"An Open-Label, Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With REGN2810 in Subjects With Newly-Diagnosed Glioblastoma (GBM)","sponsor":"Inovio Pharmaceuticals","enrolled":52,"outcomes":[]},"route":"/trials/nct03491683/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"drug":[{"id":"cemiplimab","kind":"drug","name":"Cemiplimab","route":"/drugs/cemiplimab/"},{"id":"ino-5401","kind":"drug","name":"INO-5401","route":"/drugs/ino-5401/"},{"id":"temozolomide","kind":"drug","name":"Temozolomide","route":"/drugs/temozolomide/"}],"company":[{"id":"inovio","kind":"company","name":"Inovio Pharmaceuticals","route":"/companies/inovio/"}]}}