{"entity":{"id":"nct03505320","kind":"trial","name":"A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer","aka":[],"tldr":"A phase 2 trial of Zolbetuximab, Oxaliplatin, Pembrolizumab, Leucovorin (folinic acid), Nivolumab and Docetaxel in gastric & gastro-oesophageal junction cancer, run by Astellas Pharma Global Development, Inc., active and no longer recruiting.","summary":"A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer is a phase 2 interventional study registered as NCT03505320 by Astellas Pharma Global Development, Inc., with 143 participants enrolled, started 2018-06-29 and due to reach its primary completion in 2027-06-30. Interventions recorded: zolbetuximab, oxaliplatin, leucovorin, fluorouracil, Pembrolizumab and folinic acid.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT03505320","url":"https://clinicaltrials.gov/study/NCT03505320"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["gastric"],"sections":[],"technologies":[],"targets":[],"drugs":["zolbetuximab","oxaliplatin","pembrolizumab","leucovorin","nivolumab","docetaxel"],"companies":["astellas"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT03505320","phase":"2","setting":"A Phase 2 Study of Zolbetuximab (IMAB362) as Monotherapy and in Combination With Chemotherapy and/or Immunotherapy in Subjects With Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma and Locoregional Gastric or GEJ Adenocarcinoma Whose Are Claudin (CLDN) 18.2 Positive","sponsor":"Astellas Pharma Global Development, Inc.","enrolled":143,"outcomes":[]},"route":"/trials/nct03505320/","neighbours":{"cancer":[{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"}],"drug":[{"id":"docetaxel","kind":"drug","name":"Docetaxel","route":"/drugs/docetaxel/"},{"id":"leucovorin","kind":"drug","name":"Leucovorin (folinic acid)","route":"/drugs/leucovorin/"},{"id":"nivolumab","kind":"drug","name":"Nivolumab","route":"/drugs/nivolumab/"},{"id":"oxaliplatin","kind":"drug","name":"Oxaliplatin","route":"/drugs/oxaliplatin/"},{"id":"pembrolizumab","kind":"drug","name":"Pembrolizumab","route":"/drugs/pembrolizumab/"},{"id":"zolbetuximab","kind":"drug","name":"Zolbetuximab","route":"/drugs/zolbetuximab/"}],"company":[{"id":"astellas","kind":"company","name":"Astellas","route":"/companies/astellas/"}]}}