{"entity":{"id":"nct03735290","kind":"trial","name":"A Study to Evaluate the Safety and Effectiveness of ILIxadencel Administered Into Tumors in Combination With Checkpoint Inhibitor (CPI) in Patients With ADvanced Cancer","aka":[],"tldr":"A phase 1 trial of Ilixadencel run by Mendus, terminated.","summary":"A Study to Evaluate the Safety and Effectiveness of ILIxadencel Administered Into Tumors in Combination With Checkpoint Inhibitor (CPI) in Patients With ADvanced Cancer is a phase 1 interventional study registered as NCT03735290 by Mendus, with 21 participants enrolled, started 2019-01-14. Conditions recorded: Carcinoma, Squamous Cell of Head and Neck, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma and Non-small Cell Lung Cancer. Interventions recorded: ilixadencel and Pembrolizumab.","status":"historic","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT03735290","url":"https://clinicaltrials.gov/study/NCT03735290"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck","gastric","nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["ilixadencel"],"companies":["mendus"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03735290","phase":"1","setting":"A Randomized, Open-label, Multi-center, Phase 1b/2 Trial Evaluating the Safety and Efficacy of Intratumorally-administered Ilixadencel in Combination With Checkpoint Inhibitor (CPI) in Advanced Cancer Subjects Who Are Candidates for CPI Therapy","sponsor":"Mendus","enrolled":21,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03735290/","neighbours":{"cancer":[{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"drug":[{"id":"ilixadencel","kind":"drug","name":"Ilixadencel","route":"/drugs/ilixadencel/"}],"company":[{"id":"mendus","kind":"company","name":"Mendus","route":"/companies/mendus/"}]}}