{"entity":{"id":"nct03934372","kind":"trial","name":"Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of Ponatinib in acute myeloid leukaemia, chronic myeloid leukaemia, acute lymphoblastic leukaemia and non-Hodgkin lymphoma, run by Incyte Biosciences International Sàrl, now recruiting.","summary":"Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors is a phase 1/2 interventional study registered as NCT03934372 by Incyte Biosciences International Sàrl, with 70 participants planned, started 2020-01-29 and due to reach its primary completion in 2028-02-01. Interventions recorded: Ponatinib.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT03934372","url":"https://clinicaltrials.gov/study/NCT03934372"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["aml","cml","all-leukemia","non-hodgkin-lymphoma"],"sections":[],"technologies":[],"targets":[],"drugs":["ponatinib"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT03934372","phase":"1/2","setting":"An Open-Label, Single-Arm, Phase 1/2 Study Evaluating the Safety and Efficacy of Ponatinib for the Treatment of Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors in Pediatric Participants","sponsor":"Incyte Biosciences International Sàrl","enrolled":70,"outcomes":[]},"route":"/trials/nct03934372/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"cml","kind":"cancer","name":"Chronic myeloid leukaemia (CML)","route":"/cancers/cml/"},{"id":"non-hodgkin-lymphoma","kind":"cancer","name":"Non-Hodgkin lymphoma (all types)","route":"/cancers/non-hodgkin-lymphoma/"}],"drug":[{"id":"ponatinib","kind":"drug","name":"Ponatinib","route":"/drugs/ponatinib/"}]}}