{"entity":{"id":"nct03957902","kind":"trial","name":"Assessment of Direct Biomarkers of Aspirin Action to Develop a Precision Chemoprevention Therapy of Colorectal Cancer","aka":[],"tldr":"A phase 2 trial of aspirin in colorectal cancer, run by Instituto de Investigación Sanitaria Aragón, now recruiting.","summary":"Assessment of Direct Biomarkers of Aspirin Action to Develop a Precision Chemoprevention Therapy of Colorectal Cancer is a phase 2, randomised interventional study registered as NCT03957902 by Instituto de Investigación Sanitaria Aragón, with a registry enrolment figure of 60 participants, started 2019-05-06 and due to reach its primary completion in 2025-05. Interventions recorded: acetylsalicylic acid. Conditions listed: Colorectal Cancer. Primary outcome: Assessment of changes in acetylation levels of COX enzymes in platelets and non-neoplastic and neoplastic colonic tissues. Colorectal eligibility wording from the registry: \"* recent diagnosis (\\< 48h) of rectum or colon cancer, established by endoscopy and later confirmed by anatomo-pathologic study\". Sites: Spain. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT03957902","url":"https://clinicaltrials.gov/study/NCT03957902"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["aspirin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03957902","phase":"2","setting":"Assessment of Direct Biomarkers of Aspirin Action to Develop a Precision Chemoprevention Therapy of Colorectal Cancer","sponsor":"Instituto de Investigación Sanitaria Aragón","enrolled":60,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03957902/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"drug":[{"id":"aspirin","kind":"drug","name":"Aspirin","route":"/drugs/aspirin/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}