{"entity":{"id":"nct03965234","kind":"trial","name":"Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases","aka":[],"tldr":"A phase 1/2 trial of cisplatin in colorectal cancer, run by Roswell Park Cancer Institute, now recruiting.","summary":"Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases is a phase 1/2, interventional study registered as NCT03965234 by Roswell Park Cancer Institute, with a registry enrolment figure of 99 participants, started 2020-07-16 and due to reach its primary completion in 2029-05-25. Interventions recorded: Cisplatin; Isolated Chemotherapeutic Lung Perfusion; Metastasectomy. Conditions listed: Metastatic Bone Sarcoma; Metastatic Malignant Neoplasm in the Lung; Metastatic Soft Tissue Sarcoma; Metastatic Unresectable Sarcoma; Resectable Sarcoma; Colorectal Cancer. Primary outcome: Incidence of local toxicities (Phase I); Recommended phase II dose (Phase I); Local recurrence (Phase II). Colorectal eligibility wording from the registry: \"* Colorectal carcinoma\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT03965234","url":"https://clinicaltrials.gov/study/NCT03965234"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["cytotoxic-chemotherapy","mrd-testing","platinum"],"targets":[],"drugs":["cisplatin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03965234","phase":"1/2","setting":"Phase I/ II Study of Pulmonary Suffusion to Control Minimal Residual Disease in Resectable or Ablatable Sarcoma or Colorectal Pulmonary Metastases","sponsor":"Roswell Park Cancer Institute","enrolled":99,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03965234/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"},{"id":"mrd-testing","kind":"technology","name":"MRD / molecular residual disease testing","route":"/technologies/mrd-testing/"},{"id":"platinum","kind":"technology","name":"Platinum agents","route":"/technologies/platinum/"}],"drug":[{"id":"cisplatin","kind":"drug","name":"Cisplatin","route":"/drugs/cisplatin/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}