{"entity":{"id":"nct03970746","kind":"trial","name":"Safety, Immunogenicity and Preliminary Clinical Activity Study of PDC*lung01 Cancer Vaccine in NSCLC","aka":[],"tldr":"A phase 1/2 trial of Pembrolizumab, Pemetrexed in non-small-cell lung cancer and small-cell lung cancer, run by PDC*line Pharma SAS, active and no longer recruiting.","summary":"Safety, Immunogenicity and Preliminary Clinical Activity Study of PDC*lung01 Cancer Vaccine in NSCLC is a phase 1/2 interventional study registered as NCT03970746 by PDC*line Pharma SAS, with 73 participants enrolled, started 2019-09-10 and due to reach its primary completion in 2024-07-18. Interventions recorded: PDC*lung01, Keytruda Injectable Product, Alimta Injectable Product. Conditions listed: Non Small Cell Lung Cancer. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT03970746","url":"https://clinicaltrials.gov/study/NCT03970746"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc","sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["pembrolizumab","pemetrexed"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT03970746","phase":"1/2","setting":"An Open-label, Dose-escalation, Phase I/II Study to Assess the Safety, the Tolerability, the Immunogenicity and the Preliminary Clinical Activity of the Therapeutic Cancer Vaccine, PDC*lung01, Associated or Not With Anti-PD-1 Treatment in Patients With Non-small-cell Lung Cancer (NSCLC)","sponsor":"PDC*line Pharma SAS","enrolled":73,"outcomes":[]},"route":"/trials/nct03970746/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"pembrolizumab","kind":"drug","name":"Pembrolizumab","route":"/drugs/pembrolizumab/"},{"id":"pemetrexed","kind":"drug","name":"Pemetrexed","route":"/drugs/pemetrexed/"}]}}