{"entity":{"id":"nct04095299","kind":"trial","name":"Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients","aka":["WW3"],"tldr":"A phase 3 trial in colorectal cancer, run by Vejle Hospital, now recruiting.","summary":"Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients is a phase 3, randomised interventional study registered as NCT04095299 by Vejle Hospital, with a registry enrolment figure of 162 participants, started 2020-01-20 and due to reach its primary completion in 2026-12. Interventions recorded: 50.4 Gy to the tumor and elective volume; 62 Gy to the clinical tumor volume and 50.4 Gy to the elective volume; Capecitabine 825 mg/m2 twice daily on weekdays. Conditions listed: Cancer of Rectum. Primary outcome: Rectal preservation at two years. Colorectal eligibility wording from the registry: \"* Histopathologically verified adenocarcinoma of the rectum\". Sites: Denmark. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04095299","url":"https://clinicaltrials.gov/study/NCT04095299"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04095299","phase":"3","setting":"Randomized Trial of Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy to Patients With Early Low and Mid Rectal Cancer: The Watchful Waiting 3 Trial (WW3)","sponsor":"Vejle Hospital","enrolled":162,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04095299/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}