{"entity":{"id":"nct04172597","kind":"trial","name":"A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies","aka":[],"tldr":"A phase 2 trial of Poziotinib in Breast cancer and Colorectal cancer, run by Spectrum Pharmaceuticals, Inc, recorded as terminated on the registry.","summary":"A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies is a phase 2 interventional study registered as NCT04172597 by Spectrum Pharmaceuticals, Inc, with 1 participants recorded, started 2019-12-23 and due to reach its primary completion in 2022-03-29. Interventions recorded: Poziotinib Hydrochloride, Loperamide. Conditions recorded: Breast Cancer, Colorectal Cancer, Solid Tumor, Glioblastome Multiforme.\n\nLinked to the drug Poziotinib because the registry names it among its interventions and Breast cancer and Colorectal cancer among its conditions. Registry record only: no result has been read by an editor.","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT04172597","url":"https://clinicaltrials.gov/study/NCT04172597"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["breast-cancer","colorectal"],"sections":[],"technologies":[],"targets":[],"drugs":["poziotinib"],"companies":["spectrum-pharmaceuticals"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04172597","phase":"2","setting":"A Phase 2 Study of Poziotinib in Patients With EGFR or HER2 Activating Mutations in Advanced Malignancies","sponsor":"Spectrum Pharmaceuticals, Inc","enrolled":1,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04172597/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"}],"drug":[{"id":"poziotinib","kind":"drug","name":"Poziotinib","route":"/drugs/poziotinib/"}],"company":[{"id":"spectrum-pharmaceuticals","kind":"company","name":"Spectrum Pharmaceuticals","route":"/companies/spectrum-pharmaceuticals/"}]}}