{"entity":{"id":"nct04188145","kind":"trial","name":"A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Meta","aka":["BEVAMAINT"],"tldr":"A phase 3 trial of bevacizumab (glioblastoma use) in colorectal cancer, run by Centre Hospitalier Universitaire Dijon, active but no longer recruiting.","summary":"A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Metastatic Colorectal Cancer is a phase 3, randomised interventional study registered as NCT04188145 by Centre Hospitalier Universitaire Dijon, with a registry enrolment figure of 400 participants, started 2020-01-27 and due to reach its primary completion in 2029-09. Interventions recorded: Fluoropyrimidine; Bevacizumab. Conditions listed: Metastatic Colorectal Cancer. Primary outcome: The Time-to-Treatment Failure (TTF). Colorectal eligibility wording from the registry: \"* Histologically confirmed metastatic colorectal adenocarcinoma before induction treatment\". Sites: France. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04188145","url":"https://clinicaltrials.gov/study/NCT04188145"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["bevacizumab-glioma"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04188145","phase":"3","setting":"A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Metastatic Colorectal Cancer","sponsor":"Centre Hospitalier Universitaire Dijon","enrolled":400,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04188145/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"drug":[{"id":"bevacizumab-glioma","kind":"drug","name":"Bevacizumab (glioblastoma use)","route":"/drugs/bevacizumab-glioma/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}