{"entity":{"id":"nct04195347","kind":"trial","name":"Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase","aka":[],"tldr":"A phase 1/2 trial in pancreatic cancer, run by St. Jude Children's Research Hospital, now recruiting.","summary":"Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase is a phase 1/2, interventional study registered as NCT04195347 by St. Jude Children's Research Hospital, with a registry enrolment figure of 42 participants, started 2020-09-04 and due to reach its primary completion in 2027-01. Interventions recorded: CM4620. Conditions listed: Acute Pancreatitis. Primary outcome: The number of CTCAE grade 3-5 events; Responses to CM4620. Pancreatic eligibility wording from the registry: \"* Acute pancreatitis with elevation of amylase OR lipase ≥ 3x the upper limit of normal AND at least 1 of: abdominal pain consistent with acute pancreatitis OR imaging findings consistent with acute pancreatitis\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04195347","url":"https://clinicaltrials.gov/study/NCT04195347"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04195347","phase":"1/2","setting":"CRSPA: Phase I/II Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase","sponsor":"St. Jude Children's Research Hospital","enrolled":42,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04195347/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}