{"entity":{"id":"nct04230187","kind":"trial","name":"Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer","aka":["TRIBE-C"],"tldr":"A phase 3 trial in colorectal cancer, run by Yanhong Deng, active but no longer recruiting.","summary":"Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer is a phase 3, randomised interventional study registered as NCT04230187 by Yanhong Deng, with a registry enrolment figure of 528 participants, started 2020-09-01 and due to reach its primary completion in 2026-09-01. Interventions recorded: mFOLFOXIRI plus Bevacizumab; mFOLFOX6 Plus Bevacizumab. Conditions listed: Colorectal Cancer. Primary outcome: Progression-free survival (PFS). Colorectal eligibility wording from the registry: \"\\- Histological or cytological documentation of adenocarcinoma of the colon or rectum\". Sites: China. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04230187","url":"https://clinicaltrials.gov/study/NCT04230187"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04230187","phase":"3","setting":"Bevacizumab Plus mFOLFOXIRI or mFOLFOX-6 as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer: a Randomised, Open-label, Phase 3 Trial","sponsor":"Yanhong Deng","enrolled":528,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04230187/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}