{"entity":{"id":"nct04273061","kind":"trial","name":"Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity","aka":["CAPTIV-8"],"tldr":"A phase 2 trial of atezolizumab in lung cancer, run by British Columbia Cancer Agency, now recruiting.","summary":"Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity is a phase 2, interventional study registered as NCT04273061 by British Columbia Cancer Agency, with a registry enrolment figure of 50 participants, started 2020-06-17 and due to reach its primary completion in 2027-10. Interventions recorded: Atezolizumab. Conditions listed: Breast Cancer; Lung Cancer; Gastrointestinal Cancer; Genitourinary Cancer; Gynecologic Cancer; Sarcoma; Unknown Primary Tumors; Head and Neck Cancer; Skin Cancer. Primary outcome: Overall response rate (ORR) for the study cohort, as defined by RECIST 1.1. Sites: Canada. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT04273061","url":"https://clinicaltrials.gov/study/NCT04273061"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["lung-cancer"],"sections":[],"technologies":["checkpoint-inhibitor"],"targets":[],"drugs":["atezolizumab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04273061","phase":"2","setting":"Canadian Atezolizumab Precision Targeting for Immunotherapy Intervention","sponsor":"British Columbia Cancer Agency","enrolled":50,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04273061/","neighbours":{"cancer":[{"id":"lung-cancer","kind":"cancer","name":"Lung cancer (all types)","route":"/cancers/lung-cancer/"}],"technology":[{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"}],"drug":[{"id":"atezolizumab","kind":"drug","name":"Atezolizumab","route":"/drugs/atezolizumab/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}