{"entity":{"id":"nct04293094","kind":"trial","name":"Study of AMG 650 in Adult Participants With Advanced Solid Tumors","aka":[],"tldr":"A phase 1 trial of Sovilnesib run by Volastra Therapeutics, Inc., completed.","summary":"Study of AMG 650 in Adult Participants With Advanced Solid Tumors is a phase 1 interventional study registered as NCT04293094 by Volastra Therapeutics, Inc., with 66 participants enrolled, started 2020-03-11, primary completion reached 2022-10-24. Conditions recorded: Advanced Solid Tumors. Interventions recorded: AMG 650.","status":"completed","asOf":"2026-11-04","links":[{"label":"ClinicalTrials.gov NCT04293094","url":"https://clinicaltrials.gov/study/NCT04293094"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":["sovilnesib"],"companies":["volastra-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04293094","phase":"1","setting":"A Phase 1, Multicenter, Open-label, Dose-Exploration and Dose-Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 650 in Subjects With Advanced Solid Tumors","sponsor":"Volastra Therapeutics, Inc.","enrolled":66,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04293094/","neighbours":{"drug":[{"id":"sovilnesib","kind":"drug","name":"Sovilnesib","route":"/drugs/sovilnesib/"}],"company":[{"id":"volastra-therapeutics","kind":"company","name":"Volastra Therapeutics","route":"/companies/volastra-therapeutics/"}]}}