{"entity":{"id":"nct04570943","kind":"trial","name":"Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer","aka":["GABRINOX-ART"],"tldr":"A phase 2 trial in pancreatic cancer, run by Institut du Cancer de Montpellier - Val d'Aurelle, now recruiting.","summary":"Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer is a phase 2, interventional study registered as NCT04570943 by Institut du Cancer de Montpellier - Val d'Aurelle, with a registry enrolment figure of 103 participants, started 2021-06-16 and due to reach its primary completion in 2028-01. Interventions recorded: Gabrinox; MRI-GUIDED STEREOTACTIC RADIOTHERAPY. Conditions listed: Locally Advanced Pancreatic Adenocarcinoma. Primary outcome: Rate of non-progression at 4 months; Acute gastrointestinal non-toxicity rate. Pancreatic eligibility wording from the registry: \"Histologically or cytologically proven pancreatic adenocarcinoma\". Sites: France. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04570943","url":"https://clinicaltrials.gov/study/NCT04570943"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac"],"sections":[],"technologies":["sbrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04570943","phase":"2","setting":"Phase II Study to Assess the Interest of a Sequential Treatment With Gemcitabine/Nab-paclitaxel (GEMBRAX) and Then FOLFIRINOX Followed by Stereotactic Magnetic Resonance-guided Adaptive Radiotherapy in Patients With Locally Advanced Pancreatic Cancer","sponsor":"Institut du Cancer de Montpellier - Val d'Aurelle","enrolled":103,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04570943/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"}],"technology":[{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}