{"entity":{"id":"nct04643366","kind":"trial","name":"Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Virginia Commonwealth University, now recruiting.","summary":"Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer is a phase 2, interventional study registered as NCT04643366 by Virginia Commonwealth University, with a registry enrolment figure of 64 participants, started 2021-01-28 and due to reach its primary completion in 2030-01-31. Interventions recorded: Chemotherapy; Radiation Therapy. Conditions listed: Rectal Cancer. Primary outcome: Three-year disease free survival (DFS). Colorectal eligibility wording from the registry: \"* Pathologic diagnosis of adenocarcinoma of the rectum (diagnosis by tissue biopsy) within 90 days prior to registration\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04643366","url":"https://clinicaltrials.gov/study/NCT04643366"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04643366","phase":"2","setting":"Phase 2 Study of Total Neoadjuvant mFOLFOX and Short-Course Radiotherapy in Resectable Rectal Cancer","sponsor":"Virginia Commonwealth University","enrolled":64,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04643366/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}