{"entity":{"id":"nct04680260","kind":"trial","name":"OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer","aka":["OPTIMISE"],"tldr":"A phase 2 trial in colorectal cancer, run by Karen-Lise Garm Spindler, now recruiting.","summary":"OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer is a phase 2, randomised interventional study registered as NCT04680260 by Karen-Lise Garm Spindler, with a registry enrolment figure of 350 participants, started 2021-10-25 and due to reach its primary completion in 2027-03-01. Interventions recorded: Standard of care; Circulating tumor DNA guided treatment approach. Conditions listed: Colorectal Cancer; Metastatic Cancer. Primary outcome: Recurrence Free Rate. Sites: Denmark. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04680260","url":"https://clinicaltrials.gov/study/NCT04680260"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["mrd-testing"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04680260","phase":"2","setting":"OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer - a ctDNA Guided Phase II Randomized Approach","sponsor":"Karen-Lise Garm Spindler","enrolled":350,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04680260/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"mrd-testing","kind":"technology","name":"MRD / molecular residual disease testing","route":"/technologies/mrd-testing/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}