{"entity":{"id":"nct04683315","kind":"trial","name":"PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples","aka":["PANCREAS"],"tldr":"A phase 2 trial in pancreatic cancer, run by Medical College of Wisconsin, now recruiting.","summary":"PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples is a phase 2, interventional study registered as NCT04683315 by Medical College of Wisconsin, with a registry enrolment figure of 84 participants, started 2021-04-01 and due to reach its primary completion in 2027-12-31. Interventions recorded: mFOLFIRINOX Treatment Regimen; Gemcitabine/Nab-paclitaxel Treatment Regimen. Conditions listed: Pancreatic Cancer. Primary outcome: Subjects who receive PurIST classification-directed therapy.. Pancreatic eligibility wording from the registry: \"Have suspicion of pancreas adenocarcinoma and plan for endoscopic biopsy\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04683315","url":"https://clinicaltrials.gov/study/NCT04683315"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["resectable-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04683315","phase":"2","setting":"PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples","sponsor":"Medical College of Wisconsin","enrolled":84,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04683315/","neighbours":{"cancer":[{"id":"resectable-pdac","kind":"cancer","name":"Resectable pancreatic ductal adenocarcinoma","route":"/cancers/resectable-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}