{"entity":{"id":"nct04687631","kind":"trial","name":"Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases","aka":[],"tldr":"A phase 3 trial in colorectal cancer, run by Fudan University, now recruiting.","summary":"Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases is a phase 3, randomised interventional study registered as NCT04687631 by Fudan University, with a registry enrolment figure of 508 participants, started 2021-01-14 and due to reach its primary completion in 2025-03-31. Interventions recorded: mFOLFOXIRI plus Cetuximab; mFOLFOXIRI Plus Bevacizumab. Conditions listed: Colorectal Cancer; Liver Metastases. Primary outcome: Conversion resection rate of liver metastases. Colorectal eligibility wording from the registry: \"The primary tumor was confirmed by histology as colorectal adenocarcinoma\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04687631","url":"https://clinicaltrials.gov/study/NCT04687631"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04687631","phase":"3","setting":"Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases: mFOLFOXIRI Plus Cetuximab Versus mFOLFOXIRI Plus Bevacizumab","sponsor":"Fudan University","enrolled":508,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04687631/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}