{"entity":{"id":"nct04714983","kind":"trial","name":"DNX-2440 for Resectable Colorectal Liver Metastasis","aka":[],"tldr":"A phase 1 trial of DNX-2440 run by DNAtrix, Inc., suspended.","summary":"DNX-2440 for Resectable Colorectal Liver Metastasis is a phase 1 interventional study registered as NCT04714983 by DNAtrix, Inc., with 30 participants planned, started 2021-02-15. Conditions recorded: Liver Metastases, Liver Metastasis Colon Cancer, Colorectal Cancer, Breast Cancer, Gastric Cancer, Periampullary Cancer, Melanoma, Renal Cell Cancer, Sarcoma, Squamous Cell Carcinoma and Gastrointestinal Stromal Tumors. Interventions recorded: DNX-2440.","status":"historic","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT04714983","url":"https://clinicaltrials.gov/study/NCT04714983"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","colorectal","breast-cancer","gastric","ampullary","melanoma","rcc","sarcoma","gist"],"sections":[],"technologies":[],"targets":[],"drugs":["dnx-2440"],"companies":["dnatrix"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04714983","phase":"1","setting":"A Phase I Safety and Window-of-opportunity Study of Preoperative Intratumoral Injection of OX40-ligand Expressing Oncolytic Adenovirus (DNX-2440) in Patients With Resectable Liver Metastasis","sponsor":"DNAtrix, Inc.","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04714983/","neighbours":{"cancer":[{"id":"ampullary","kind":"cancer","name":"Ampullary cancer (ampulla of Vater)","route":"/cancers/ampullary/"},{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"gist","kind":"cancer","name":"Gastrointestinal stromal tumour (GIST)","route":"/cancers/gist/"},{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"rcc","kind":"cancer","name":"Renal cell carcinoma","route":"/cancers/rcc/"},{"id":"sarcoma","kind":"cancer","name":"Sarcomas (soft tissue, bone, GIST)","route":"/cancers/sarcoma/"}],"drug":[{"id":"dnx-2440","kind":"drug","name":"DNX-2440","route":"/drugs/dnx-2440/"}],"company":[{"id":"dnatrix","kind":"company","name":"DNAtrix","route":"/companies/dnatrix/"}]}}