{"entity":{"id":"nct04792489","kind":"trial","name":"DALY II USA/ MB-CART2019.1 for DLBCL","aka":[],"tldr":"A phase 2 trial of Zamtocabtagene autoleucel, Cyclophosphamide, Fludarabine in diffuse large b-cell lymphoma and mantle cell lymphoma, run by Miltenyi Biomedicine GmbH, now recruiting.","summary":"DALY II USA/ MB-CART2019.1 for DLBCL is a phase 2 interventional study registered as NCT04792489 by Miltenyi Biomedicine GmbH, with 315 participants planned, started 2021-05-25 and due to reach its primary completion in 2026-12-31. Interventions recorded: zamtocabtagene autoleucel (MB-CART2019.1), Cyclophosphamide, Fludarabine, Bendamustine. Conditions listed: Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B Cell Lymphoma, High Grade B-cell Lymphoma (HGBCL), Primary Mediastinal B-cell Lymphoma (PMBCL). No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT04792489","url":"https://clinicaltrials.gov/study/NCT04792489"}],"tags":["ctgov-ingest"],"related":[],"cancers":["dlbcl","mantle-cell-lymphoma"],"sections":[],"technologies":[],"targets":[],"drugs":["zamtocabtagene-autoleucel","cyclophosphamide","fludarabine","bendamustine"],"companies":["miltenyi-biomedicine"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT04792489","phase":"2","setting":"A Multi-center Single Arm Phase II Study to Evaluate the Safety and Efficacy of Genetically Engineered Autologous Cells Expressing Anti-CD20 and Anti-CD19 Specific Chimeric Antigen Receptor in Subjects With Relapsed and/or Refractory Diffuse Large B Cell Lymphoma","sponsor":"Miltenyi Biomedicine GmbH","enrolled":315,"outcomes":[]},"route":"/trials/nct04792489/","neighbours":{"cancer":[{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"},{"id":"mantle-cell-lymphoma","kind":"cancer","name":"Mantle cell lymphoma","route":"/cancers/mantle-cell-lymphoma/"}],"drug":[{"id":"bendamustine","kind":"drug","name":"Bendamustine","route":"/drugs/bendamustine/"},{"id":"cyclophosphamide","kind":"drug","name":"Cyclophosphamide","route":"/drugs/cyclophosphamide/"},{"id":"fludarabine","kind":"drug","name":"Fludarabine","route":"/drugs/fludarabine/"},{"id":"zamtocabtagene-autoleucel","kind":"drug","name":"Zamtocabtagene autoleucel","route":"/drugs/zamtocabtagene-autoleucel/"}],"company":[{"id":"miltenyi-biomedicine","kind":"company","name":"Miltenyi Biomedicine","route":"/companies/miltenyi-biomedicine/"}]}}