{"entity":{"id":"nct04821141","kind":"trial","name":"Bazedoxifene plus conjugated estrogens for breast risk biomarkers","aka":["Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens"],"tldr":"This study compares bazedoxifene plus conjugated estrogens with a waiting-list group. It measures breast cancer risk markers and menopausal symptoms, rather than treating an existing breast cancer.","summary":"This study compares bazedoxifene plus conjugated estrogens with a waiting-list group. It measures breast cancer risk markers and menopausal symptoms, rather than treating an existing breast cancer.\n\nInterventional study registered as NCT04821141, sponsored by University of Kansas Medical Center. Registry phase: 2. Registry enrollment is 120 participants (estimated). Registry status checked October 10, 2026: active not recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.","status":"active","asOf":"2026-10-10","links":[{"label":"ClinicalTrials.gov NCT04821141","url":"https://clinicaltrials.gov/study/NCT04821141"},{"label":"UCSF study listing and local availability","url":"https://clinicaltrials.ucsf.edu/trial/NCT04821141"}],"tags":["ucsf-breast-coverage","interventional"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["ucsf"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04821141","phase":"2","setting":"Women at increased breast cancer risk with menopausal symptoms","sponsor":"University of Kansas Medical Center","participation":[{"nct":"NCT04821141","source":"https://clinicaltrials.gov/study/NCT04821141","fetchedAt":"2026-10-10T20:54:20.582402Z","studySha256":"357c0577c4b8297fcff62e6b36df5b9868738f6127cc3f64eb32d06813cf4f1f","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2025-10-29","leadSponsor":"University of Kansas Medical Center","collaboratorCount":1,"minimumAge":"45 Years","maximumAge":"64 Years","sex":"FEMALE","healthyVolunteers":true,"hasEligibility":true,"enrolment":120,"enrolmentType":"ESTIMATED","siteCount":6,"recruitingSiteCount":0,"countries":["United States"]}],"started":"2021-12-14","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04821141/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"institution":[{"id":"ucsf","kind":"institution","name":"UCSF Helen Diller Family Comprehensive Cancer Center","route":"/institutions/ucsf/"}]}}