{"entity":{"id":"nct04842617","kind":"trial","name":"Phase III Study ：SHR6390/Placebo Combined With Endocrine Therapy for the Adjuvant Treatment of Hormone Receptor Positive,Human Epidermal Receptor 2 Ne","aka":[],"tldr":"A phase 3 trial of Dalpiciclib in male breast cancer, run by Jiangsu HengRui Medicine Co., Ltd., active and no longer recruiting.","summary":"Phase III Study ：SHR6390/Placebo Combined With Endocrine Therapy for the Adjuvant Treatment of Hormone Receptor Positive,Human Epidermal Receptor 2 Negative is a phase 3 interventional study registered as NCT04842617 by Jiangsu HengRui Medicine Co., Ltd., with 5274 participants enrolled, started 2021-04-30 and due to reach its primary completion in 2026-10-31. Interventions recorded: SHR6390, placebo. Conditions listed: Hormone Receptor Positive,Human Epidermal Receptor 2 Negative, Node-positive, High Risk, Early Stage，Female Breast Cancer. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT04842617","url":"https://clinicaltrials.gov/study/NCT04842617"}],"tags":["ctgov-ingest"],"related":[],"cancers":["male-breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["dalpiciclib"],"companies":["hengrui"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT04842617","phase":"3","setting":"A Multicenter, Randomized, Double-blind Phase III Study：SHR6390/Placebo Combined With Endocrine Therapy for the Adjuvant Treatment of Hormone Receptor Positive,Human Epidermal Receptor 2 Negative, Node-positive, High Risk, Early Stage，Female Breast Cancer","sponsor":"Jiangsu HengRui Medicine Co., Ltd.","enrolled":5274,"outcomes":[]},"route":"/trials/nct04842617/","neighbours":{"cancer":[{"id":"male-breast-cancer","kind":"cancer","name":"Male breast cancer","route":"/cancers/male-breast-cancer/"}],"drug":[{"id":"dalpiciclib","kind":"drug","name":"Dalpiciclib","route":"/drugs/dalpiciclib/"}],"company":[{"id":"hengrui","kind":"company","name":"Jiangsu Hengrui Pharmaceuticals","route":"/companies/hengrui/"}]}}