{"entity":{"id":"nct04928807","kind":"trial","name":"Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION)","aka":[],"tldr":"A phase 3 trial in colorectal cancer, run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, active but no longer recruiting.","summary":"Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION) is a phase 3, randomised interventional study registered as NCT04928807 by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, with a registry enrolment figure of 231 participants, started 2021-07-20 and due to reach its primary completion in 2023-03-01. Interventions recorded: Short course radiotherapy sequential camrelizumab and chemotherapy. Conditions listed: Rectal Cancer. Primary outcome: pathological complete response (pCR) rate. Colorectal eligibility wording from the registry: \"Histologically confirmed T3-44 and/or N+ rectal adenocarcinoma (AJCC/UICC TNM staging (8th Edition, 2017);\". Sites: China. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04928807","url":"https://clinicaltrials.gov/study/NCT04928807"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":["hengrui"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04928807","phase":"3","setting":"A Multicenter, Randomized, Open-label, Controlled Phase III Clinical Trial of Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in the Treatment for Locally Advanced Rectal Cancer","sponsor":"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology","enrolled":231,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04928807/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"company":[{"id":"hengrui","kind":"company","name":"Jiangsu Hengrui Pharmaceuticals","route":"/companies/hengrui/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}