{"entity":{"id":"nct04988555","kind":"trial","name":"A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)","aka":[],"tldr":"A phase 1/2 trial of Venetoclax, Gilteritinib, Azacitidine in multiple myeloma, run by Sumitomo Pharma America, Inc., now recruiting.","summary":"A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1) is a phase 1/2 interventional study registered as NCT04988555 by Sumitomo Pharma America, Inc., with 606 participants planned, started 2022-02-28 and due to reach its primary completion in 2027-06-30. Interventions recorded: Enzomenib, azoles, Venetoclax, Gilteritinib, Azacitidine (AZA). Conditions listed: Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute, Multiple Myeloma, Myelodysplastic Syndromes. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT04988555","url":"https://clinicaltrials.gov/study/NCT04988555"}],"tags":["ctgov-ingest"],"related":[],"cancers":["multiple-myeloma"],"sections":[],"technologies":[],"targets":[],"drugs":["venetoclax","gilteritinib","azacitidine"],"companies":["sumitomo-pharma"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT04988555","phase":"1/2","setting":"A Phase 1/2, Open-Label, Dose-Escalation, Dose-Expansion Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia and Other Selected Hematologic Malignancies, With and Without Mixed Lineage Leukemia (MLL) Rearrangement or Nucleophosmin 1 (NPM1) Mutation (Horizen-1)","sponsor":"Sumitomo Pharma America, Inc.","enrolled":606,"outcomes":[]},"route":"/trials/nct04988555/","neighbours":{"cancer":[{"id":"multiple-myeloma","kind":"cancer","name":"Multiple myeloma","route":"/cancers/multiple-myeloma/"}],"drug":[{"id":"azacitidine","kind":"drug","name":"Azacitidine","route":"/drugs/azacitidine/"},{"id":"gilteritinib","kind":"drug","name":"Gilteritinib","route":"/drugs/gilteritinib/"},{"id":"venetoclax","kind":"drug","name":"Venetoclax","route":"/drugs/venetoclax/"}],"company":[{"id":"sumitomo-pharma","kind":"company","name":"Sumitomo Pharma (Myovant)","route":"/companies/sumitomo-pharma/"}]}}