{"entity":{"id":"nct04990609","kind":"trial","name":"EUS-RFA PANCARDINAL-1 Trial","aka":[],"tldr":"A phase 2 trial in pancreatic cancer, run by The University of Texas Health Science Center, Houston, now recruiting.","summary":"EUS-RFA PANCARDINAL-1 Trial is a phase 2, interventional study registered as NCT04990609 by The University of Texas Health Science Center, Houston, with a registry enrolment figure of 60 participants, started 2021-08-13 and due to reach its primary completion in 2026-12-01. Interventions recorded: Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA); Neoadjuvant Chemotherapy (NAC). Conditions listed: Pancreatic Ductal Adenocarcinoma (PDAC). Primary outcome: Number of participants who are able to complete neoadjuvant chemotherapy plus EUS-RFA and later undergo surgical tumor resection. Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04990609","url":"https://clinicaltrials.gov/study/NCT04990609"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04990609","phase":"2","setting":"A Single-arm Phase II Study to Evaluate the Safety and Efficacy of Combination Systematic Chemotherapy and Multiple Rounds of Endoscopic Ultrasound-guided Radiofrequency Ablation in Pancreatic Cancer","sponsor":"The University of Texas Health Science Center, Houston","enrolled":60,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04990609/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}