{"entity":{"id":"nct05006716","kind":"trial","name":"A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies","aka":[],"tldr":"A phase 1/2 trial of BGB-16673 in follicular lymphoma and hodgkin lymphoma, run by BeOne Medicines, now recruiting.","summary":"A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies is a phase 1/2 interventional study registered as NCT05006716 by BeOne Medicines, with 645 participants planned, started 2021-09-13 and due to reach its primary completion in 2026-11. Interventions recorded: Tacabrutideg. Conditions listed: B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05006716","url":"https://clinicaltrials.gov/study/NCT05006716"}],"tags":["ctgov-ingest"],"related":[],"cancers":["follicular-lymphoma","hodgkin-lymphoma","non-hodgkin-lymphoma","mantle-cell-lymphoma","dlbcl"],"sections":[],"technologies":[],"targets":[],"drugs":["bgb-16673"],"companies":["beone"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT05006716","phase":"1/2","setting":"A Phase 1/2, Open-Label, Dose-Escalation and -Expansion Study of the Bruton Tyrosine Kinase Targeted Protein Degrader BGB-16673 in Patients With B-Cell Malignancies","sponsor":"BeOne Medicines","enrolled":645,"outcomes":[]},"route":"/trials/nct05006716/","neighbours":{"cancer":[{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"},{"id":"follicular-lymphoma","kind":"cancer","name":"Follicular lymphoma","route":"/cancers/follicular-lymphoma/"},{"id":"hodgkin-lymphoma","kind":"cancer","name":"Hodgkin lymphoma","route":"/cancers/hodgkin-lymphoma/"},{"id":"mantle-cell-lymphoma","kind":"cancer","name":"Mantle cell lymphoma","route":"/cancers/mantle-cell-lymphoma/"},{"id":"non-hodgkin-lymphoma","kind":"cancer","name":"Non-Hodgkin lymphoma (all types)","route":"/cancers/non-hodgkin-lymphoma/"}],"drug":[{"id":"bgb-16673","kind":"drug","name":"BGB-16673","route":"/drugs/bgb-16673/"}],"company":[{"id":"beone","kind":"company","name":"BeOne Medicines (formerly BeiGene)","route":"/companies/beone/"}]}}