{"entity":{"id":"nct05016349","kind":"trial","name":"Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer","aka":[],"tldr":"A phase 3 trial of Tretinoin, Mifepristone, Alitretinoin and Tamoxifen in Breast cancer, run by Mahmoud Ramadan mohamed Elkazzaz, with a status the registry has not verified recently.","summary":"Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer is a phase 3 interventional study registered as NCT05016349 by Mahmoud Ramadan mohamed Elkazzaz, with 160 participants planned, started 2021-08 and due to reach its primary completion in 2021-10. Interventions recorded: All trans-retinoic acid, 13-Cis Retinoic Acid plus Tocopherol, Mifepristone, Cannabidiol, 9 cis retinoic acid, Tamoxifen, Standard therapy. Conditions recorded: Breast Cancer Female.\n\nLinked to the drug Alitretinoin because the registry names it among its interventions and Breast cancer among its conditions. Registry record only: no result has been read by an editor.","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT05016349","url":"https://clinicaltrials.gov/study/NCT05016349"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["tretinoin-atra","mifepristone","alitretinoin","tamoxifen"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05016349","phase":"3","setting":"Why Antiprogestrone (Mifepristone) and Cyp 26 Inhibitor Must be Combined With Tamoxifen or ( Tamoxifen and Retinoic Acid) for Treating Early Breast Cancer","sponsor":"Mahmoud Ramadan mohamed Elkazzaz","enrolled":160,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05016349/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"drug":[{"id":"alitretinoin","kind":"drug","name":"Alitretinoin","route":"/drugs/alitretinoin/"},{"id":"mifepristone","kind":"drug","name":"Mifepristone","route":"/drugs/mifepristone/"},{"id":"tamoxifen","kind":"drug","name":"Tamoxifen","route":"/drugs/tamoxifen/"},{"id":"tretinoin-atra","kind":"drug","name":"Tretinoin (all-trans retinoic acid, ATRA)","route":"/drugs/tretinoin-atra/"}]}}