{"entity":{"id":"nct05076682","kind":"trial","name":"Reverse Triple Negative Immune Resistant Breast Cancer","aka":[],"tldr":"A phase 2 trial of Trastuzumab rezetecan, SHR-A2102, Adebrelimab and Mecapegfilgrastim in Triple-negative breast cancer, run by Fudan University, now recruiting.","summary":"Reverse Triple Negative Immune Resistant Breast Cancer is a phase 2 interventional study registered as NCT05076682 by Fudan University, with 80 participants planned, started 2022-06-30 and due to reach its primary completion in 2026-12-31. Interventions recorded: Choline, anti-PD-1 antibody and chemotherapy, Sodium Cromoglicate, Efavirenz, SHR-A1811, SHR-A2102, SHR-1316, Mecapegfilgrastim, AK131, Theophylline. Conditions recorded: Triple-negative Breast Cancer.\n\nLinked to the drug Mecapegfilgrastim because the registry names it among its interventions and Triple-negative breast cancer among its conditions. Registry record only: no result has been read by an editor.","status":"recruiting","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT05076682","url":"https://clinicaltrials.gov/study/NCT05076682"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["tnbc"],"sections":[],"technologies":[],"targets":[],"drugs":["trastuzumab-rezetecan","shr-a2102","adebrelimab","mecapegfilgrastim"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05076682","phase":"2","setting":"Reverse Triple Negative Immune Resistant Breast Cancer","sponsor":"Fudan University","enrolled":80,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05076682/","neighbours":{"cancer":[{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"drug":[{"id":"adebrelimab","kind":"drug","name":"Adebrelimab","route":"/drugs/adebrelimab/"},{"id":"mecapegfilgrastim","kind":"drug","name":"Mecapegfilgrastim","route":"/drugs/mecapegfilgrastim/"},{"id":"shr-a2102","kind":"drug","name":"SHR-A2102","route":"/drugs/shr-a2102/"},{"id":"trastuzumab-rezetecan","kind":"drug","name":"Trastuzumab rezetecan","route":"/drugs/trastuzumab-rezetecan/"}]}}