{"entity":{"id":"nct05083247","kind":"trial","name":"Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma","aka":["STEREOPAC"],"tldr":"A phase 2 trial in pancreatic cancer, run by Erasme University Hospital, now recruiting.","summary":"Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma is a phase 2, randomised interventional study registered as NCT05083247 by Erasme University Hospital, with a registry enrolment figure of 256 participants, started 2023-03-24 and due to reach its primary completion in 2027-12-31. Interventions recorded: mFOLFIRINOX or Gemcitabine nab-paclitaxel; Isotoxic High-Dose (iHD)-SBRT; Surgery. Conditions listed: Pancreatic Neoplasm; Pancreatic Adenocarcinoma; Borderline Resectable Pancreatic Adenocarcinoma. Primary outcome: Disease free survival; R0 Resection rate. Pancreatic eligibility wording from the registry: \"* Cytologic or histologic proof of adenocarcinoma of the pancreatic head or uncinated process or body or tail\". Sites: Belgium. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05083247","url":"https://clinicaltrials.gov/study/NCT05083247"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["borderline-resectable-pdac","resectable-pdac"],"sections":[],"technologies":["sbrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05083247","phase":"2","setting":"Preoperative Treatment With mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose Stereotactic Body Radiation Therapy (iHD-SBRT) for Borderline Resectable Pancreatic Adenocarcinoma: a Randomised Phase II Study (STEREOPAC)","sponsor":"Erasme University Hospital","enrolled":256,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05083247/","neighbours":{"cancer":[{"id":"borderline-resectable-pdac","kind":"cancer","name":"Borderline resectable pancreatic ductal adenocarcinoma","route":"/cancers/borderline-resectable-pdac/"},{"id":"resectable-pdac","kind":"cancer","name":"Resectable pancreatic ductal adenocarcinoma","route":"/cancers/resectable-pdac/"}],"technology":[{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}