{"entity":{"id":"nct05116072","kind":"trial","name":"Efficacy and Safety of TPIAT for Resectable Adenocarcinoma of the Pancreas Region at High Risk of Postoperative Fistula","aka":["TPIAT-01"],"tldr":"A phase 1/2 trial in pancreatic cancer, run by University Hospital, Lille, now recruiting.","summary":"Efficacy and Safety of TPIAT for Resectable Adenocarcinoma of the Pancreas Region at High Risk of Postoperative Fistula is a phase 1/2, interventional study registered as NCT05116072 by University Hospital, Lille, with a registry enrolment figure of 36 participants, started 2022-02-20 and due to reach its primary completion in 2028-02-20. Interventions recorded: total pancreatectomy; intraportal islet autotransplantation. Conditions listed: Adenocarcinoma of the Pancreas; Adenocarcinoma of the Duodenum; Ampullary Adenocarcinoma. Primary outcome: the rate of patients who have completed the chemotherapy planned. Pancreatic eligibility wording from the registry: \"Inclusion criteria are composed of preoperative conditions validated by intraoperative confirmation to plan an exit of the protocol if the pancreas does not finally appear with a high-risk of CR-POPF\". Sites: France. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05116072","url":"https://clinicaltrials.gov/study/NCT05116072"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["resectable-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05116072","phase":"1/2","setting":"Efficacy and Safety of Total Pancreatectomy With Intraportal Islet Autotransplantation for Resectable Adenocarcinoma of the Cephalic Region of the Pancreas at High-risk of Postoperative Fistula and Requiring Systemic Adjuvant Chemotherapy","sponsor":"University Hospital, Lille","enrolled":36,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05116072/","neighbours":{"cancer":[{"id":"resectable-pdac","kind":"cancer","name":"Resectable pancreatic ductal adenocarcinoma","route":"/cancers/resectable-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}