{"entity":{"id":"nct05120271","kind":"trial","name":"BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of CAR-GPC3 T Cells in hepatocellular carcinoma, non-small-cell lung cancer, merkel cell carcinoma and sarcomas, run by Sotio Biotech Inc., active and no longer recruiting.","summary":"BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors is a phase 1/2 interventional study registered as NCT05120271 by Sotio Biotech Inc., with 7 participants enrolled, started 2022-10-26 and due to reach its primary completion in 2025-10-24. Interventions recorded: CAR-GPC3 T Cells.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05120271","url":"https://clinicaltrials.gov/study/NCT05120271"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["hcc","nsclc","merkel-cell-carcinoma","sarcoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["sotio"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT05120271","phase":"1/2","setting":"A First-in-Human, Phase 1/2, Dose Escalation Study of BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors","sponsor":"Sotio Biotech Inc.","enrolled":7,"outcomes":[]},"route":"/trials/nct05120271/","neighbours":{"cancer":[{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"merkel-cell-carcinoma","kind":"cancer","name":"Merkel cell carcinoma","route":"/cancers/merkel-cell-carcinoma/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sarcoma","kind":"cancer","name":"Sarcomas (soft tissue, bone, GIST)","route":"/cancers/sarcoma/"}],"company":[{"id":"sotio","kind":"company","name":"SOTIO Biotech","route":"/companies/sotio/"}]}}