{"entity":{"id":"nct05186506","kind":"trial","name":"A Study Comparing Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer","aka":[],"tldr":"A phase 2 trial in lung cancer, run by Sichuan University, not yet recruiting.","summary":"A Study Comparing Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer is a phase 2, randomised interventional study registered as NCT05186506 by Sichuan University, with a registry enrolment figure of 152 participants, started 2022-01-01 and due to reach its primary completion in 2025-12-15. Interventions recorded: Ensatinib; chemotherapy. Conditions listed: ALK Fusion Protein Expression; Adjuvant Therapy; Non-Small Cell Lung Cancer. Primary outcome: Disease free survival (DFS). Lung eligibility wording from the registry: \"* Surgical resection of histologically confirmed Stage IIA to IIIA NSCLC with negative margins, ,within 10 weeks after the operation\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT05186506","url":"https://clinicaltrials.gov/study/NCT05186506"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["alk-positive-nsclc","resectable-nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["betta"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05186506","phase":"2","setting":"A Phase II, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer","sponsor":"Sichuan University","enrolled":152,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05186506/","neighbours":{"cancer":[{"id":"alk-positive-nsclc","kind":"cancer","name":"ALK-positive non-small-cell lung cancer","route":"/cancers/alk-positive-nsclc/"},{"id":"resectable-nsclc","kind":"cancer","name":"Resectable stage I to III non-small-cell lung cancer","route":"/cancers/resectable-nsclc/"}],"company":[{"id":"betta","kind":"company","name":"Betta Pharmaceuticals","route":"/companies/betta/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}