{"entity":{"id":"nct05194878","kind":"trial","name":"Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers","aka":[],"tldr":"A phase 3 trial in colorectal cancer, run by Sun Yat-sen University, now recruiting.","summary":"Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers is a phase 3, randomised interventional study registered as NCT05194878 by Sun Yat-sen University, with a registry enrolment figure of 840 participants, started 2021-12-01 and due to reach its primary completion in 2024-12. Interventions recorded: neoadjuvant chemotherapyI; Colectomy; adjuvant chemotherapy. Conditions listed: Colon Cancer Stage II; Colon Cancer Stage III. Primary outcome: Disease-free survival. Colorectal eligibility wording from the registry: \"* Histologically proven adenocarcinoma or high grade dysplasia on histology plus unequivocal radiological evidence of invasive cancer of the colon(≥ 12 cm from the anal verge)\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05194878","url":"https://clinicaltrials.gov/study/NCT05194878"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05194878","phase":"3","setting":"Phase III Study of Neoadjuvant FOLFOXIRI Chemotherapy Versus Immediate Surgery for High-risk Resectable Stage II and III Colon Cancers","sponsor":"Sun Yat-sen University","enrolled":840,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05194878/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}