{"entity":{"id":"nct05239143","kind":"trial","name":"P-MUC1C-ALLO1 in advanced solid tumors","aka":["P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors"],"tldr":"This early study tests donor-derived immune cells engineered to recognize a tumor-associated protein. It evaluates dose and safety across selected advanced solid tumors.","summary":"This early study tests donor-derived immune cells engineered to recognize a tumor-associated protein. It evaluates dose and safety across selected advanced solid tumors.\n\nInterventional study registered as NCT05239143, sponsored by Poseida Therapeutics, Inc.. Registry phase: 1. Registry enrollment is 180 participants (estimated). Registry status checked October 10, 2026: active not recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.","status":"active","asOf":"2026-10-10","links":[{"label":"ClinicalTrials.gov NCT05239143","url":"https://clinicaltrials.gov/study/NCT05239143"},{"label":"UCSF study listing and local availability","url":"https://clinicaltrials.ucsf.edu/trial/NCT05239143"}],"tags":["ucsf-breast-coverage","interventional"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["ucsf"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05239143","phase":"1","setting":"Advanced or metastatic epithelial solid tumors","sponsor":"Poseida Therapeutics, Inc.","participation":[{"nct":"NCT05239143","source":"https://clinicaltrials.gov/study/NCT05239143","fetchedAt":"2026-10-10T20:54:21.948989Z","studySha256":"c3d762db3fc7a89298b3c4b7b87e30588573cac396c7a69fdf8b7ad022ebae87","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2026-02-09","leadSponsor":"Poseida Therapeutics, Inc.","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":180,"enrolmentType":"ESTIMATED","siteCount":14,"recruitingSiteCount":0,"countries":["United States"]}],"started":"2022-02-15","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05239143/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"institution":[{"id":"ucsf","kind":"institution","name":"UCSF Helen Diller Family Comprehensive Cancer Center","route":"/institutions/ucsf/"}]}}