{"entity":{"id":"nct05247684","kind":"trial","name":"AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLC","aka":[],"tldr":"A phase 2 trial of Ivonescimab, Carboplatin, Cisplatin in non-small-cell lung cancer and small-cell lung cancer, run by Akeso, active and no longer recruiting.","summary":"AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLC is a phase 2 interventional study registered as NCT05247684 by Akeso, with 90 participants enrolled, started 2022-02-20 and due to reach its primary completion in 2025-08-18. Interventions recorded: AK112, Carboplatin, Cisplatin, Paclitaxel. Conditions listed: Resectable Non-small Cell Lung Cancer. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05247684","url":"https://clinicaltrials.gov/study/NCT05247684"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc","sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["ivonescimab","carboplatin","cisplatin","paclitaxel"],"companies":["akeso"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT05247684","phase":"2","setting":"Phase II Clinical Study of AK112, an Anti-PD-1 and VEGF Bispecific Antibody, Alone or in Combination With Chemotherapy for the Neoadjuvant/Adjuvant Treatment of Resectable Non-small Cell Lung Cancer","sponsor":"Akeso","enrolled":90,"outcomes":[]},"route":"/trials/nct05247684/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"carboplatin","kind":"drug","name":"Carboplatin","route":"/drugs/carboplatin/"},{"id":"cisplatin","kind":"drug","name":"Cisplatin","route":"/drugs/cisplatin/"},{"id":"ivonescimab","kind":"drug","name":"Ivonescimab","route":"/drugs/ivonescimab/"},{"id":"paclitaxel","kind":"drug","name":"Paclitaxel / nab-paclitaxel","route":"/drugs/paclitaxel/"}],"company":[{"id":"akeso","kind":"company","name":"Akeso","route":"/companies/akeso/"}]}}