{"entity":{"id":"nct05283226","kind":"trial","name":"Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck","aka":[],"tldr":"A phase 2 trial of Paclitaxel / nab-paclitaxel in head and neck squamous cell carcinoma, run by NATCO Pharma Ltd., now recruiting.","summary":"Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy is a phase 2 interventional study registered as NCT05283226 by NATCO Pharma Ltd., with 21 participants planned, started 2022-09-30 and due to reach its primary completion in 2026-12-30. Interventions recorded: NRC-2694-A, Paclitaxel. Conditions listed: Carcinoma, Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05283226","url":"https://clinicaltrials.gov/study/NCT05283226"}],"tags":["ctgov-ingest"],"related":[],"cancers":["head-and-neck"],"sections":[],"technologies":[],"targets":[],"drugs":["paclitaxel"],"companies":["natco"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT05283226","phase":"2","setting":"A Phase 2 Multicenter, Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy","sponsor":"NATCO Pharma Ltd.","enrolled":21,"outcomes":[]},"route":"/trials/nct05283226/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"}],"drug":[{"id":"paclitaxel","kind":"drug","name":"Paclitaxel / nab-paclitaxel","route":"/drugs/paclitaxel/"}],"company":[{"id":"natco","kind":"company","name":"Natco Pharma","route":"/companies/natco/"}]}}