{"entity":{"id":"nct05296681","kind":"trial","name":"Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Howard S. Hochster, MD, now recruiting.","summary":"Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery is a phase 2, randomised interventional study registered as NCT05296681 by Howard S. Hochster, MD, with a registry enrolment figure of 42 participants, started 2022-05-03 and due to reach its primary completion in 2026-12. Interventions recorded: NBT-NM108. Conditions listed: Metastatic Colon Carcinoma; Stage IV Colon Cancer AJCC v8; Stage IVA Colon Cancer AJCC v8; Stage IVB Colon Cancer AJCC v8; Stage IVC Colon Cancer AJCC v8. Primary outcome: The number of participants with treatment-related Adverse Events as Assessed by Cancer Therapy Evaluation Program Common Toxicity Criteria (CTCAE) Version 5.0 for toxicity and Adverse Event reporting; Tumor Response by RECIST v1.1 Criteria. Colorectal eligibility wording from the registry: \"* Biopsy proven and metastatic colon cancer\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05296681","url":"https://clinicaltrials.gov/study/NCT05296681"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05296681","phase":"2","setting":"A Randomized Trial of Microbiotic Product (NBT-NM108) to Promote Microbiome Health and Improve Chemotherapy Delivery","sponsor":"Howard S. Hochster, MD","enrolled":42,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05296681/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}