{"entity":{"id":"nct05393466","kind":"trial","name":"BPI-361175 Tablets in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)","aka":[],"tldr":"A phase 1/2 trial in lung cancer, run by Xcovery Holdings, Inc., not yet recruiting.","summary":"BPI-361175 Tablets in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) is a phase 1/2, interventional study registered as NCT05393466 by Xcovery Holdings, Inc., with a registry enrolment figure of 30 participants, started 2026-07-01 and due to reach its primary completion in 2028-01-30. Interventions recorded: BPI-361175. Conditions listed: Non-small Cell Lung Carcinoma. Primary outcome: The percentage of patients with adverse events and serious adverse events graded per National Cancer Institute Common Terminology Criteria for Adverse Events and dose limiting toxicities for BPI 361175; Efficacy of BPI-361175. Lung eligibility wording from the registry: \"Patients with histologically or cytologically confirmed diagnosis of inoperable locally advanced or recurrent/metastatic NSCLC with EGFR mutations\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT05393466","url":"https://clinicaltrials.gov/study/NCT05393466"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["xcovery"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05393466","phase":"1/2","setting":"A Phase I/II, Open-label Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of BPI-361175 Tablets in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)","sponsor":"Xcovery Holdings, Inc.","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05393466/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"company":[{"id":"xcovery","kind":"company","name":"Xcovery","route":"/companies/xcovery/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}