{"entity":{"id":"nct05491512","kind":"trial","name":"A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer","aka":[],"tldr":"A phase 2 trial of F-MISO (JBS-003) run by Memorial Sloan Kettering Cancer Center, now recruiting.","summary":"A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer is a phase 2 interventional study registered as NCT05491512 by Memorial Sloan Kettering Cancer Center, with 121 participants planned, started 2022-08-04. Conditions recorded: HPV, Throat Cancer, Oropharyngeal Carcinoma, Oropharyngeal Cancer and Human Papilloma Virus. Interventions recorded: 18 F-FMISO PET/CT, Radiation, Cisplatin, Carboplatin and 5-fluorouracil.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT05491512","url":"https://clinicaltrials.gov/study/NCT05491512"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck","oropharyngeal-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["jbs-003"],"companies":["juniper-biosciences"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05491512","phase":"2","setting":"Major Radiation Dose De-Escalation Concurrent With Chemotherapy for Human Papilloma Virus Associated Oropharyngeal Carcinoma","sponsor":"Memorial Sloan Kettering Cancer Center","enrolled":121,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05491512/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"oropharyngeal-cancer","kind":"cancer","name":"Oropharyngeal cancer (tonsil and base of tongue)","route":"/cancers/oropharyngeal-cancer/"}],"drug":[{"id":"jbs-003","kind":"drug","name":"F-MISO (JBS-003)","route":"/drugs/jbs-003/"}],"company":[{"id":"juniper-biosciences","kind":"company","name":"Juniper Biosciences","route":"/companies/juniper-biosciences/"}]}}