{"entity":{"id":"nct05534087","kind":"trial","name":"Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer (KCSG CO22-12)","aka":["CLAUDIA"],"tldr":"A phase 3 trial in colorectal cancer, run by Seoul National University Hospital, now recruiting.","summary":"Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer (KCSG CO22-12) is a phase 3, randomised interventional study registered as NCT05534087 by Seoul National University Hospital, with a registry enrolment figure of 236 participants, started 2022-12-15 and due to reach its primary completion in 2028-09-30. Interventions recorded: mFOLFIRINOX-FOLFIRI intensified chemotherapy; FOLFOX or CAPOX adjuvant chemotherapy. Conditions listed: Colon Cancer. Primary outcome: 3-year disease-free survival rate. Colorectal eligibility wording from the registry: \"Adenocarcinoma of colon confirmed by histology\". Sites: South Korea. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05534087","url":"https://clinicaltrials.gov/study/NCT05534087"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":["mrd-testing"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05534087","phase":"3","setting":"A Randomized Controlled Phase III Trial of Treatment Intensification in Stage II-III Colon Cancer Patients With Positive MRD During Adjuvant Chemotherapy","sponsor":"Seoul National University Hospital","enrolled":236,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05534087/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"technology":[{"id":"mrd-testing","kind":"technology","name":"MRD / molecular residual disease testing","route":"/technologies/mrd-testing/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}