{"entity":{"id":"nct05546268","kind":"trial","name":"Study of Oral MRT-2359 in Selected Cancer Patients","aka":[],"tldr":"A phase 1/2 trial of Oral MRT-2359 in non-small-cell lung cancer, small-cell lung cancer, neuroendocrine tumours, HR-positive / HER2-negative breast cancer and prostate cancer, run by Monte Rosa Therapeutics, Inc, active and no longer recruiting.","summary":"Study of Oral MRT-2359 in Selected Cancer Patients is a phase 1/2 interventional study registered as NCT05546268 by Monte Rosa Therapeutics, Inc, with 174 participants enrolled, started 2022-10-12 and due to reach its primary completion in 2026-05. Interventions recorded: Oral MRT-2359.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05546268","url":"https://clinicaltrials.gov/study/NCT05546268"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["nsclc","sclc","neuroendocrine","breast-hr-positive","prostate"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["monte-rosa"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT05546268","phase":"1/2","setting":"A Phase 1/2 Study of Oral MRT-2359 in Patients With MYC-Driven and Other Selected Solid Tumors Including Lung Cancer and Diffuse B-Cell Lymphoma","sponsor":"Monte Rosa Therapeutics, Inc","enrolled":174,"outcomes":[]},"route":"/trials/nct05546268/","neighbours":{"cancer":[{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"neuroendocrine","kind":"cancer","name":"Neuroendocrine tumours","route":"/cancers/neuroendocrine/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"company":[{"id":"monte-rosa","kind":"company","name":"Monte Rosa Therapeutics","route":"/companies/monte-rosa/"}]}}