{"entity":{"id":"nct05550415","kind":"trial","name":"The Role of Simvastatin in The Epithelial-Mesenchymal Transition Process of Breast Cancer","aka":[],"tldr":"A phase 2 trial in triple-negative breast cancer, run by Universitas Indonesia, now recruiting.","summary":"The Role of Simvastatin in The Epithelial-Mesenchymal Transition Process of Breast Cancer is a phase 2, randomised interventional study registered as NCT05550415 by Universitas Indonesia, with a registry enrolment figure of 26 participants, started 2022-08-19 and due to reach its primary completion in 2026-11. Interventions recorded: Simvastatin 40mg; Placebo. Conditions listed: Triple Negative Breast Cancer; Chemotherapy Effect; Simvastatin Adverse Reaction. Triple-negative eligibility wording from the registry: \"Female patients with advanced breast cancer (locally advanced and distantly advanced) with triple-negative molecular type confirmed by biopsy and immunohistochemical examination\". Sites: Indonesia. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05550415","url":"https://clinicaltrials.gov/study/NCT05550415"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-metastatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05550415","phase":"2","setting":"Vimentin Expression-based Therapeutic Response in Triple Negative Breast Cancer Receiving Combination of Simvastatin and NAC: A Randomized, Double-Blind, Placebo-Controlled Trial","sponsor":"Universitas Indonesia","enrolled":26,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05550415/","neighbours":{"cancer":[{"id":"tnbc-metastatic","kind":"cancer","name":"Metastatic triple-negative breast cancer","route":"/cancers/tnbc-metastatic/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}