{"entity":{"id":"nct05555251","kind":"trial","name":"BI-1607 in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of BI-1607 run by BioInvent International AB, terminated.","summary":"BI-1607 in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT05555251 by BioInvent International AB, with 18 participants enrolled, started 2022-07-28. Conditions recorded: HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2-positive Metastatic Breast Cancer, Metastatic Gastroesophageal Junction Adenocarcinoma and Metastatic Gastric Adenocarcinoma. Interventions recorded: BI-1607, BI-1607 and Trastuzumab.","status":"historic","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT05555251","url":"https://clinicaltrials.gov/study/NCT05555251"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["breast-her2-positive","gastric-her2-positive","gastric"],"sections":[],"technologies":[],"targets":[],"drugs":["bi-1607"],"companies":["bioinvent-international"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05555251","phase":"1/2","setting":"Phase 1/2a Open-label Clinical Trial of BI-1607, an Fc-Engineered Monoclonal Antibody to CD32b (FcγRIIB), in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors","sponsor":"BioInvent International AB","enrolled":18,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05555251/","neighbours":{"cancer":[{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"breast-her2-positive","kind":"cancer","name":"HER2-positive breast cancer","route":"/cancers/breast-her2-positive/"},{"id":"gastric-her2-positive","kind":"cancer","name":"HER2-positive gastric cancer","route":"/cancers/gastric-her2-positive/"}],"drug":[{"id":"bi-1607","kind":"drug","name":"BI-1607","route":"/drugs/bi-1607/"}],"company":[{"id":"bioinvent-international","kind":"company","name":"BioInvent International","route":"/companies/bioinvent-international/"}]}}