{"entity":{"id":"nct05563922","kind":"trial","name":"Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma","aka":["OP-TNT"],"tldr":"A phase 2 trial in colorectal cancer, run by Shanghai Zhongshan Hospital, now recruiting.","summary":"Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma is a phase 2, interventional study registered as NCT05563922 by Shanghai Zhongshan Hospital, with a registry enrolment figure of 56 participants, started 2022-09-01 and due to reach its primary completion in 2025-08-31. Interventions recorded: Total Neoadjuvant Chemoradiotherapy. Conditions listed: Rectal Cancer. Primary outcome: Organ preservation rate at 3 years. Colorectal eligibility wording from the registry: \"* cT1-3N0M0 assessed by CT, MRI and ultrasound colonoscopy\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05563922","url":"https://clinicaltrials.gov/study/NCT05563922"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05563922","phase":"2","setting":"Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Early Low Rectal Carcinoma: A Prospective, Exploratory Trial","sponsor":"Shanghai Zhongshan Hospital","enrolled":56,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05563922/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}