{"entity":{"id":"nct05577702","kind":"trial","name":"Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations in Participants With Resectable Non-Small Cell Lung Cancer","aka":[],"tldr":"A phase 2 trial of Alcestobart run by BeiGene, completed.","summary":"Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations in Participants With Resectable Non-Small Cell Lung Cancer is a phase 2 interventional study registered as NCT05577702 by BeiGene, with 121 participants enrolled, started 2023-03-08. Conditions recorded: Non Small Cell Lung Cancer. Interventions recorded: Tislelizumab, Ociperlimab, Alcestobart, Cisplatin, Carboplatin, Pemetrexed and Paclitaxel.","status":"completed","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT05577702","url":"https://clinicaltrials.gov/study/NCT05577702"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["alcestobart"],"companies":["nanjing-leads-biolabs"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05577702","phase":"2","setting":"A Randomized, Open-Label, Multicenter, Phase 2, Umbrella Study to Evaluate the Preliminary Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations With and Without Chemotherapy as Neoadjuvant Treatment in Chinese Patients With Resectable Stage II to IIIA Non-Small Cell Lung Cancer","sponsor":"BeiGene","enrolled":121,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05577702/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"drug":[{"id":"alcestobart","kind":"drug","name":"Alcestobart","route":"/drugs/alcestobart/"}],"company":[{"id":"nanjing-leads-biolabs","kind":"company","name":"Nanjing Leads Biolabs","route":"/companies/nanjing-leads-biolabs/"}]}}