{"entity":{"id":"nct05578326","kind":"trial","name":"Study of Trilaciclib and Lurbinectidin","aka":[],"tldr":"A phase 2 trial of trilaciclib and lurbinectedin in lung cancer, run by UNC Lineberger Comprehensive Cancer Center, now recruiting.","summary":"Study of Trilaciclib and Lurbinectidin is a phase 2, interventional study registered as NCT05578326 by UNC Lineberger Comprehensive Cancer Center, with a registry enrolment figure of 30 participants, started 2022-10-12 and due to reach its primary completion in 2026-12-25. Interventions recorded: Trilaciclib; Lurbinectedin. Conditions listed: Lung Cancer; Small-cell Lung Cancer. Primary outcome: The proportion of grade 4 neutropenia; The duration of grade 4 neutropenia. Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT05578326","url":"https://clinicaltrials.gov/study/NCT05578326"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["sclc"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["trilaciclib","lurbinectedin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05578326","phase":"2","setting":"Study of Trilaciclib and Lurbinectedin in Small Cell Lung Cancer","sponsor":"UNC Lineberger Comprehensive Cancer Center","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05578326/","neighbours":{"cancer":[{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"lurbinectedin","kind":"drug","name":"Lurbinectedin","route":"/drugs/lurbinectedin/"},{"id":"trilaciclib","kind":"drug","name":"Trilaciclib","route":"/drugs/trilaciclib/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}