{"entity":{"id":"nct05620134","kind":"trial","name":"Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer","aka":[],"tldr":"A phase 1/2 trial of JK08, Pembrolizumab in metastatic cancer and melanoma, run by Salubris Biotherapeutics Inc, active and no longer recruiting.","summary":"Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer is a phase 1/2 interventional study registered as NCT05620134 by Salubris Biotherapeutics Inc, with 263 participants planned, started 2022-10-17 and due to reach its primary completion in 2025-10-17. Interventions recorded: JK08, Pembrolizumab, Lenvatinib Pill. Conditions listed: Cancer, Tumor, Solid, Advanced Solid Tumor, Metastatic Cancer. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05620134","url":"https://clinicaltrials.gov/study/NCT05620134"}],"tags":["ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","melanoma","colorectal","nsclc","sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["jk08","pembrolizumab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT05620134","phase":"1/2","setting":"A Phase 1/2, Multicenter, Open Label, Dose Escalation & Dose Expansion Study of JK08, an IL-15 Antibody Fusion Protein Targeting CTLA-4, Monotherapy or in Combination in Patients with Unresectable Locally Advanced or Metastatic Cancer","sponsor":"Salubris Biotherapeutics Inc","enrolled":263,"outcomes":[]},"route":"/trials/nct05620134/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"jk08","kind":"drug","name":"JK08","route":"/drugs/jk08/"},{"id":"pembrolizumab","kind":"drug","name":"Pembrolizumab","route":"/drugs/pembrolizumab/"}]}}